Flash Photolysis of Caged Compounds: Casting Light on Physiological Processes.
نویسندگان
چکیده
Photorelease of bioactive molecules from inactive precursors is a very powerful tool for the study of the molecular mechanisms underlying physiological processes as diverse as ionic channel modulation, exocytosis, phototransduction, ligand-receptor interaction, and cross-bridge activity. A brief account of the methodology, available compounds, and fields of application is presented here.
منابع مشابه
Flash photolysis of caged compounds
Photolabile ‘caged’ compounds are biologically inert precursors of active molecules, which when irradiated with a pulse of light free the active species at its site of action (see Fig. 1). Speed is the principal advantage offered by these probes; photochemical reactions can be very fast, with release of the active species often complete within a millisecond. The method can thus be used to study...
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ورودعنوان ژورنال:
- News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
دوره 13 شماره
صفحات -
تاریخ انتشار 1998